Mutagens
- Name
- Mutagens
- Accession Number
- DBCAT000955
- Description
Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
- Drugs
Drug Drug Description Cyclophosphamide A nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma. Dantron A drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx. Lacidipine A lipophilic dihydropyridine calcium channel blocker with a slow onset of action used to treat hypertension. Hydroquinone A topical brightening agent used for the treatment of skin disorders associated with hyperpigmentation including melasma, post-inflammatory hyperpigmentation, sunspots, and freckles. Aminacrine A slow-acting germicide effective against bacteria and fungi which is included in drug formulations for its anti-septic properties. Benznidazole A trypanocidal agent used to treat Chagas disease. Cordycepin Cordycepin has been used in trials studying the treatment of Leukemia. Trofosfamide Trofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors. Carbendazim Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific. Thiram Thiram may be used in dermatology as a scabicide . Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for... Sodium bisulfite An ingredient in parenteral nutrition products for patients with severe liver disorders. p-Aminophenol Not Annotated 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science of Pancreas Cancer. Patulin Not Annotated Emoxypine Emoxypine is under investigation in clinical trial NCT06221826 (MEXIDOL® in the Rehabilitation Treatment of Patients With Acute Cerebral Failure). - Drugs & Drug Targets