Fibric Acids
- Name
- Fibric Acids
- Accession Number
- DBCAT001018 (DBCAT002705)
- Description
Compounds that either share the structure of fibric acid in their molecular arrangement or are considered variants of the fibric acid structure.
- ATC Classification
- Drugs
Drug Drug Description Clofibrate A fibric acid derivative used to treat hypertriglyceridemia and high cholesterol. Gemfibrozil A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. Bezafibrate A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. Etofibrate Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations. Simfibrate Not Annotated Clofibride Not Annotated Fenofibric acid A fibrate used to treat severe hypertriglyceridemia, primary hypercholesterolemia, or mixed dyslipidemia. Fenofibrate A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. Ciprofibrate Not Annotated Ronifibrate Not Annotated Aluminium clofibrate Not Annotated Pemafibrate Pemafibrate is under investigation in clinical trial NCT03350165 (A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)). - Drugs & Drug Targets