Sphingosine-1-phosphate (S1P) receptor modulators

All categories
Name
Sphingosine-1-phosphate (S1P) receptor modulators
Accession Number
DBCAT005916
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
FingolimodA sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19.
PonesimodA sphingosine 1-phosphate receptor modulator indicated to treat relapsing multiple sclerosis.
SiponimodA medication used to treat relapsing multiple sclerosis.
OzanimodA sphingosine 1-phosphate receptor modulator being studied to treat Multiple Sclerosis (MS) and inflammatory bowel disease (IBD).
EtrasimodAn S1P receptors modulator used to treat moderate to severely active ulcerative colitis in adults
Drugs & Drug Targets
DrugTargetType
FingolimodSphingosine 1-phosphate receptor 5target
FingolimodSphingosine kinase 1enzyme
FingolimodCytochrome P450 2E1enzyme
FingolimodLeukotriene-B(4) omega-hydroxylase 1enzyme
FingolimodHistone deacetylase 1target
FingolimodExcitatory amino acid transporter 2transporter
FingolimodExcitatory amino acid transporter 1transporter
FingolimodP-glycoprotein 1transporter
FingolimodMultidrug resistance-associated protein 1transporter
FingolimodSphingosine 1-phosphate receptor 1target
FingolimodSphingosine 1-phosphate receptor 4target
FingolimodSphingosine 1-phosphate receptor 3target
PonesimodSphingosine 1-phosphate receptor 1target
PonesimodCytochrome P450 2J2enzyme
PonesimodCytochrome P450 3A4enzyme
PonesimodCytochrome P450 3A5enzyme
PonesimodCytochrome P450 4F3enzyme
PonesimodCytochrome P450 4F12enzyme
PonesimodUDP-glucuronosyltransferase 1-1enzyme
PonesimodUDP-glucuronosyltransferase 2B7enzyme
SiponimodSphingosine 1-phosphate receptor 5target
SiponimodSphingosine 1-phosphate receptor 1target
SiponimodCytochrome P450 3A4enzyme
SiponimodCytochrome P450 2C9enzyme
OzanimodSphingosine 1-phosphate receptor 1target
OzanimodSphingosine 1-phosphate receptor 5target
OzanimodAmine oxidase [flavin-containing] Btransporter
OzanimodATP-binding cassette sub-family G member 2transporter
OzanimodP-glycoprotein 1transporter
OzanimodFatty aldehyde dehydrogenaseenzyme
OzanimodAlcohol dehydrogenase class-3enzyme
OzanimodArylamine N-acetyltransferase 2enzyme
OzanimodCytochrome P450 2C8enzyme
OzanimodAmine oxidase [flavin-containing] Benzyme
OzanimodAldo-keto reductase family 1 member C1enzyme
OzanimodAldo-keto reductase family 1 member C2enzyme
OzanimodCytochrome P450 3A4enzyme
EtrasimodCytochrome P450 2C8enzyme
EtrasimodCytochrome P450 2C9enzyme
EtrasimodCytochrome P450 2C19enzyme
EtrasimodCytochrome P450 2J2enzyme
EtrasimodCytochrome P450 3A4enzyme
EtrasimodSphingosine 1-phosphate receptor 1target
EtrasimodSphingosine 1-phosphate receptor 4target
EtrasimodSphingosine 1-phosphate receptor 5target