Disorders of urea cycle metabolism
Also known as: Urea Cycle Disorder / Disorder of the Urea Cycle / Urea Cycle Disorders / Disorder of urea cycle metabolism, unspecified / Urea Cycle Disorders, Inborn / Disorder of the urea cycle metabolism (disorder)
Drug | Drug Name | Drug Description |
---|---|---|
DB00125 | Arginine | An amino acid commonly found as a component of total parenteral nutrition. |
DB08909 | Glycerol phenylbutyrate | A nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions. |
DB06819 | Phenylbutyric acid | An agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy. |
Drug | Drug Name | Phase | Status | Count |
---|---|---|---|---|
DB08909 | Glycerol phenylbutyrate | 1 | Completed | 1 |
DB17667 | SYNB1020 | 1 | Completed | 1 |
DB00551 | Acetohydroxamic acid | 1 / 2 | Terminated | 1 |
DB17695 | Heterologous human adult liver derived progenitor cells | 1 / 2 | Completed | 1 |
DB00125 | Arginine | 2 | Completed | 1 |
DB06170 | Glycerol phenylbutyrate | 2 | Completed | 1 |
DB08909 | Glycerol phenylbutyrate | 2 | Completed | 1 |
DB17695 | Heterologous human adult liver derived progenitor cells | 2 | Completed | 2 |
DB17695 | Heterologous human adult liver derived progenitor cells | 2 | Withdrawn | 1 |
DB06819 | Phenylbutyric acid | 2 | Completed | 2 |
DB06170 | Glycerol phenylbutyrate | 3 | Completed | 2 |
DB08909 | Glycerol phenylbutyrate | 3 | Completed | 1 |
DB06819 | Phenylbutyric acid | 3 | Completed | 1 |
DB08909 | Glycerol phenylbutyrate | 4 | Completed | 3 |
DB06819 | Phenylbutyric acid | 4 | Completed | 1 |