Systemic Mastocytosis
Also known as: Mastocytosis, Systemic / Systemic mastocytosis (morphologic abnormality) / Malignant systemic mastocytosis (morphologic abnormality) / Systemic mast cell disease (disorder) / Isolated bone marrow mastocytosis (disorder) / Smoldering systemic mastocytosis (morphologic abnormality) / Smoldering systemic mastocytosis (disorder) / Indolent Systemic Mastocytosis / Indolent systemic mastocytosis (morphologic abnormality) / Indolent systemic mastocytosis (disorder)
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB00501 | Cimetidine | A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. |
| DB06595 | Midostaurin | An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). |
| DB00338 | Omeprazole | A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. |
| DB00863 | Ranitidine | A histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis. |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB00316 | Acetaminophen | 1 | Active Not Recruiting | 1 |
| DB01234 | Dexamethasone | 1 | Active Not Recruiting | 1 |
| DB01075 | Diphenhydramine | 1 | Active Not Recruiting | 1 |
| DB15223 | Flotetuzumab | 1 | Active Not Recruiting | 1 |
| DB01050 | Ibuprofen | 1 | Active Not Recruiting | 1 |
| DB00863 | Ranitidine | 1 | Active Not Recruiting | 1 |
| DB18494 | GTB-3550 | 1 / 2 | Terminated | 1 |
| DB04868 | Nilotinib | 1 / 2 | Completed | 1 |
| DB18041 | Bezuclastinib | 2 | Recruiting | 1 |
| DB08870 | Brentuximab vedotin | 2 | Completed | 1 |
| DB01254 | Dasatinib | 2 | Unknown Status | 1 |
| DB00004 | Denileukin diftitox | 2 | Completed | 1 |
| DB01590 | Everolimus | 2 | Completed | 1 |
| DB15223 | Flotetuzumab | 2 | Withdrawn | 1 |
| DB09053 | Ibrutinib | 2 | Terminated | 1 |
| DB00619 | Imatinib | 2 | Completed | 1 |
| DB12191 | Obatoclax | 2 | Terminated | 1 |
| DB11105 | Benzalkonium | 2 / 3 | Unknown Status | 1 |
| DB00242 | Cladribine | 2 / 3 | Unknown Status | 1 |
| DB06643 | Denosumab | 3 | Completed | 1 |
| DB00619 | Imatinib | 4 | Completed | 1 |