Relapsed or Refractory Acute Myeloid Leukemia With FLT3 Activating Mutations

Drug	Drug Name	Drug Description
DB12141	Gilteritinib	An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.

Drug	Drug Name	Target	Type
DB12141	Gilteritinib	Albumin	carrier
DB12141	Gilteritinib	Cytochrome P450 3A4	enzyme
DB12141	Gilteritinib	Receptor-type tyrosine-protein kinase FLT3	target
DB12141	Gilteritinib	Serotonin Receptors	target
DB12141	Gilteritinib	ATP-dependent translocase ABCB1	transporter
DB12141	Gilteritinib	Multidrug and toxin extrusion protein 1	transporter
DB12141	Gilteritinib	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
DB12141	Gilteritinib	Solute carrier family 22 member 1	transporter
DB12141	Gilteritinib	Tyrosine-protein kinase receptor UFO	target
DB12141	Gilteritinib	ALK tyrosine kinase receptor	target

Drug	Drug Name	Phase	Status	Count
DB11832	Crenolanib	2	Completed	1