Perennial Allergic Rhinitis (PAR)

Also known as: Perennial Allergic Rhinitis / Rhinitis, Allergic, Perennial / Other allergic rhinitis / Perennial allergic rhinitis (disorder) / Allergic rhinitis, unspecified / Allergic rhinosinusitis / Rhinallergosis / Rhinitis allergic / Rhinitis allergic NOS / Allergic rhinitis / Allergic rhinitis (disorder) / Rhinitis, Allergic

DrugDrug NameDrug Description
DB00972AzelastineA histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
DB00394Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
DB00341CetirizineA selective Histamine-1 antagonist drug used in allergic rhinitis and chronic urticaria.
DB01410CiclesonideA glucocorticoid used in the symptomatic relief of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents.
DB01380Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
DB01003Cromoglicic acidA medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions.
DB00434CyproheptadineA combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome.
DB00967DesloratadineA second generation tricyclic antihistamine used to treat seasonal and non seasonal allergic rhinitis, pruritus, and urticaria.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB08979FenspirideAn oxazolidinone spiro compound with antispasmodic and bronchodilator effects used in the treatment of ENT and respiratory diseases.
DB00332IpratropiumAn anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
DB06282LevocetirizineAn H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria.
DB00455LoratadineA second generation antihistamine used to manage the symptoms of allergic rhinitis.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB12523MizolastineA second-generation non-sedating antihistamine used to treat symptoms of allergic rhinoconjunctivitis and urticaria.
DB00471MontelukastA leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB00427TriprolidineA sedating antihistamine combined with pseudoephedrine and guaifenesin in various types of cold and allergy medications to relieve allergy symptoms, hay fever and common cold symptoms, and to aid in sleep.
DrugDrug NameTargetType
DB00972AzelastineHistamine H1 receptortarget
DB00972AzelastineCytochrome P450 1A2enzyme
DB00972AzelastineCytochrome P450 2D6enzyme
DB00972AzelastineCytochrome P450 3A4enzyme
DB00972AzelastineCytochrome P450 2C19enzyme
DB00972AzelastineCytochrome P450 1A1enzyme
DB00972AzelastineCytochrome P450 3A5enzyme
DB00972AzelastineCytochrome P450 2C9enzyme
DB00972AzelastineCytochrome P450 2C8enzyme
DB00972AzelastineATP-dependent translocase ABCB1transporter
DB00972AzelastineCytochrome P450 2A6enzyme
DB00972AzelastineCytochrome P450 2E1enzyme
DB00972AzelastineHistamine H2 receptortarget
DB00972AzelastinePhospholipase A2target
DB00972AzelastineLeukotriene C4 synthasetarget
DB00972AzelastineCytochrome P450 2B6enzyme
DB00394Beclomethasone dipropionateCorticosteroid-binding globulincarrier
DB00394Beclomethasone dipropionateGlucocorticoid receptortarget
DB00394Beclomethasone dipropionateCytochrome P450 3A5enzyme
DB00394Beclomethasone dipropionateCytochrome P450 3A4enzyme
DB00394Beclomethasone dipropionateATP-dependent translocase ABCB1transporter
DB00394Beclomethasone dipropionateBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
DB00394Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
DB00341CetirizineHistamine H1 receptortarget
DB00341CetirizineATP-dependent translocase ABCB1transporter
DB01410CiclesonideCorticosteroid-binding globulincarrier
DB01410CiclesonideCytochrome P450 3A4enzyme
DB01410CiclesonideCytochrome P450 2D6enzyme
DB01410CiclesonideGlucocorticoid receptortarget
DB01410CiclesonideLiver carboxylesterase 1enzyme
DB01410CiclesonideCorticosteroid-binding globulintarget
DB01380Cortisone acetateGlucocorticoid receptortarget
DB01380Cortisone acetateCytochrome P450 3A4enzyme
DB01380Cortisone acetateCytochrome P450 3A5enzyme
DB01380Cortisone acetateAnnexin A1target
DB01380Cortisone acetateCorticosteroid-binding globulincarrier
DB01380Cortisone acetateAlbumincarrier
DB01380Cortisone acetateSolute carrier organic anion transporter family member 1A2transporter
DB01380Cortisone acetateATP-dependent translocase ABCB1transporter
DB01380Cortisone acetateOrganic anion transporter 3transporter
DB01380Cortisone acetateSteroid hormone receptor ERR1target
DB01380Cortisone acetateSteroid hormone receptor ERR2target
DB01380Cortisone acetateEstrogen-related receptor gammatarget
DB01003Cromoglicic acidProtein S100-Ptarget
DB01003Cromoglicic acidHeat shock protein HSP 90-alphatarget
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Atarget
DB00434CyproheptadineHistamine H1 receptortarget
DB00434CyproheptadineMuscarinic acetylcholine receptor M1target
DB00434CyproheptadineMuscarinic acetylcholine receptor M2target
DB00434CyproheptadineMuscarinic acetylcholine receptor M3target
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
DB00434CyproheptadineUDP-glucuronosyltransferase 1A3enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 7target
DB00434CyproheptadineUDP-glucuronosyltransferase 2B10enzyme
DB00434CyproheptadineUDP-glucuronosyltransferase 1A4enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Btarget
DB00434CyproheptadineHistamine H2 receptortarget
DB00434CyproheptadineSolute carrier family 22 member 1transporter
DB00434CyproheptadineAlbumincarrier
DB00967DesloratadineHistamine H1 receptortarget
DB00967DesloratadineATP-dependent translocase ABCB1transporter
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneATP-dependent translocase ABCB1transporter
DB01234DexamethasoneATP-binding cassette sub-family C member 2transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01234DexamethasoneAlbumincarrier
DB01234Dexamethasone11-beta-hydroxysteroid dehydrogenase type 2enzyme
DB01234Dexamethasone11-beta-hydroxysteroid dehydrogenase 1enzyme
DB01234DexamethasoneOrganic anion transporter 3transporter
DB00332IpratropiumMuscarinic acetylcholine receptor M1target
DB00332IpratropiumMuscarinic acetylcholine receptor M2target
DB00332IpratropiumMuscarinic acetylcholine receptor M3target
DB00332IpratropiumOrganic cation/carnitine transporter 2transporter
DB00332IpratropiumSolute carrier family 22 member 4transporter
DB00332IpratropiumAlbumincarrier
DB00332Ipratropiumalpha1-acid glycoproteincarrier
DB06282LevocetirizineHistamine H1 receptortarget
DB06282LevocetirizineSolute carrier family 22 member 11transporter
DB06282LevocetirizineCytochrome P450 3A4enzyme
DB06282LevocetirizineAlbumincarrier
DB00455LoratadineHistamine H1 receptortarget
DB00455LoratadineCytochrome P450 3A4enzyme
DB00455LoratadineCytochrome P450 2C19enzyme
DB00455LoratadineCytochrome P450 2D6enzyme
DB00455LoratadineCytochrome P450 2C8enzyme
DB00455LoratadineATP-dependent translocase ABCB1transporter
DB00455LoratadineVoltage-gated inwardly rectifying potassium channel KCNH2target
DB00455LoratadineBile salt export pumptransporter
DB00455LoratadineCytochrome P450 1A1enzyme
DB00455LoratadineCytochrome P450 1A2enzyme
DB00455LoratadineCytochrome P450 2B6enzyme
DB00455LoratadineCytochrome P450 2C9enzyme
DB00455LoratadineCytochrome P450 3A5enzyme
DB00455LoratadineUDP-glucuronosyltransferase 2B10enzyme
DB00455LoratadineUDP-glucuronosyltransferase 1A1enzyme
DB00455LoratadineUDP-glucuronosyltransferase 1A3enzyme
DB00455LoratadineUDP-glucuronosyltransferase 2B15enzyme
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneATP-dependent translocase ABCB1transporter
DB00959MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
DB00959MethylprednisoloneCytochrome P450 2A6enzyme
DB00959MethylprednisoloneCytochrome P450 1B1enzyme
DB00959MethylprednisoloneCytochrome P450 2B6enzyme
DB00959MethylprednisoloneCytochrome P450 2C8enzyme
DB00959MethylprednisoloneCytochrome P450 2C9enzyme
DB00959MethylprednisoloneCytochrome P450 2C19enzyme
DB00959MethylprednisoloneAnnexin A1target
DB00959Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
DB00959Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
DB00959MethylprednisoloneAlbumincarrier
DB12523MizolastineCytochrome P450 2D6enzyme
DB12523MizolastineHistamine H1 receptortarget
DB00471MontelukastCysteinyl leukotriene receptor 1target
DB00471MontelukastPolyunsaturated fatty acid 5-lipoxygenasetarget
DB00471MontelukastCytochrome P450 3A4enzyme
DB00471MontelukastCytochrome P450 2C9enzyme
DB00471MontelukastCytochrome P450 2C8enzyme
DB00471MontelukastSolute carrier organic anion transporter family member 2B1transporter
DB00471MontelukastProstaglandin G/H synthase 1enzyme
DB00471MontelukastCytochrome P450 2A6enzyme
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneATP-dependent translocase ABCB1transporter
DB00860PrednisoloneAlbumincarrier
DB00427TriprolidineHistamine H1 receptortarget
DB00427TriprolidineAlbumincarrier
DrugDrug NamePhaseStatusCount
DB00394Beclomethasone dipropionateNot AvailableCompleted1
DB00967DesloratadineNot AvailableCompleted1
DB00751EpinastineNot AvailableCompleted2
DB08906Fluticasone furoateNot AvailableCompleted1
DB08906Fluticasone furoateNot AvailableRecruiting1
DB00588Fluticasone propionateNot AvailableCompleted2
DB17412Gemogenovatucel-TNot AvailableUnknown Status1
DB00455LoratadineNot AvailableCompleted1
DB00455LoratadineNot AvailableUnknown Status1
DB14512Mometasone furoateNot AvailableCompleted1
DB00972Azelastine1Completed1
DB12524BI-6718001Completed1
DB04890Bepotastine1Completed2
DB00588Fluticasone propionate1Completed2
DB09157Carbon dioxide2Completed1
DB04983Denufosol2Completed1
DB08906Fluticasone furoate2Completed1
DB00455Loratadine2Completed1
DB14512Mometasone furoate2Completed1
DB00972Azelastine3Completed4
DB00207Azithromycin3Completed1
DB00394Beclomethasone dipropionate3Completed4
DB04890Bepotastine3Completed3
DB11591Bilastine3Completed1
DB01222Budesonide3Withdrawn2
DB00341Cetirizine3Completed6
DB01410Ciclesonide3Completed14
DB00967Desloratadine3Completed2
DB01234Dexamethasone3Completed1
DB00751Epinastine3Completed2
DB00668Epinephrine3Completed1
DB00950Fexofenadine3Completed1
DB00180Flunisolide3Completed1
DB08906Fluticasone furoate3Completed10
DB00588Fluticasone propionate3Completed3
DB00920Ketotifen3Completed2
DB16551Lactobacillus paracasei3Completed1
DB01106Levocabastine3Completed1
DB06282Levocetirizine3Completed1
DB00455Loratadine3Completed2
DB00764Mometasone3Completed4
DB14512Mometasone furoate3Completed11
DB00471Montelukast3Completed5
DB00768Olopatadine3Completed2
DB00635Prednisone3Completed1
DB00852Pseudoephedrine3Completed2
DB00620Triamcinolone3Completed1
DB00972Azelastine4Completed1
DB01222Budesonide4Completed2
DB00341Cetirizine4Completed3
DB01410Ciclesonide4Completed2
DB00967Desloratadine4Completed3
DB00950Fexofenadine4Completed1
DB08906Fluticasone furoate4Completed6
DB00588Fluticasone propionate4Completed3
DB00588Fluticasone propionate4Terminated1
DB06282Levocetirizine4Completed4
DB06282Levocetirizine4Unknown Status1
DB00455Loratadine4Completed2
DB14512Mometasone furoate4Completed1
DB14512Mometasone furoate4Terminated1
DB00471Montelukast4Completed1
DB00471Montelukast4Terminated1
DB00768Olopatadine4Completed1
DB00620Triamcinolone4Completed1