Familial Mediterranean Fever (FMF )
Also known as: Familial Mediterranean Syndrome / Familial Mediterranean Fever (FMF) / Familial Mediterranean Fever / Periodic fever syndromes / Familial Mediterranean fever (disorder) / Familial recurrent polyserositis
Drug | Drug Name | Drug Description |
---|---|---|
DB06168 | Canakinumab | An interleukin-1β blocker used to treat Periodic Fever Syndromes such as Cryopyrin-Associated Periodic Syndromes (CAPS) and Familial Mediterranean Fever (FMF), and also to treat active Systemic Juvenile Idiopathic Arthritis (SJIA). |
DB01394 | Colchicine | An alkaloid used to treat gout and Familial Mediterranean Fever as well as prevent major cardiovascular events. |
Drug | Drug Name | Target | Type |
---|---|---|---|
DB06168 | Canakinumab | Interleukin-1 beta | target |
DB01394 | Colchicine | Tubulin beta chain | target |
DB01394 | Colchicine | Cytochrome P450 3A4 | enzyme |
DB01394 | Colchicine | ATP-dependent translocase ABCB1 | transporter |
DB01394 | Colchicine | Cytochrome P450 2B6 | enzyme |
DB01394 | Colchicine | Cytochrome P450 2C8 | enzyme |
DB01394 | Colchicine | Cytochrome P450 2E1 | enzyme |
DB01394 | Colchicine | Albumin | carrier |
Drug | Drug Name | Phase | Status | Count |
---|---|---|---|---|
DB01394 | Colchicine | 1 | Completed | 1 |
DB06168 | Canakinumab | 2 | Completed | 1 |
DB16396 | Goflikicept | 2 | Recruiting | 2 |
DB06372 | Rilonacept | 2 | Completed | 2 |
DB06273 | Tocilizumab | 2 | Completed | 1 |
DB06405 | Eprodisate | 2 / 3 | Completed | 1 |
DB00026 | Anakinra | 3 | Completed | 1 |
DB01394 | Colchicine | 4 | Completed | 1 |