Mild, moderate Novel Coronavirus Infectious Disease (COVID-19)

Also known as: Mild to Moderate COVID-19 / Mild-to-moderate COVID-19

DrugDrug NameDrug Description
DB15718BamlanivimabA neutralizing human IgG1κ monoclonal antibody against the SARS-CoV-2 spike (S) protein for use in patients aged 12 and over at high risk of developing severe COVID-19.
DB15897EtesevimabEtesevimab in combination with bamlanivimab is used to treat mild to moderate coronavirus disease 2019 (COVID-19) in adults and pediatric patients, including neonates, with positive results of direct SARS-CoV-2 viral...
DB15940ImdevimabPart of an investigational recombinant monoclonal antibody cocktail used to treat mild to moderate COVID-19.
DB15661MolnupiravirAn orally bioavailable isopropylester cytidine analog used to treat COVID-19.
DB16691NirmatrelvirAn oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19.
DB14761RemdesivirA nucleoside analog used to treat RNA virus infections including COVID-19.
DB00503RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
DrugDrug NameTargetType
DB15718BamlanivimabSpike glycoproteintarget
DB15897EtesevimabSpike glycoproteintarget
DB15940ImdevimabSpike glycoproteintarget
DB16691NirmatrelvirReplicase polyprotein 1abtarget
DB16691NirmatrelvirCytochrome P450 3A4enzyme
DB16691NirmatrelvirATP-dependent translocase ABCB1transporter
DB14761RemdesivirReplicase polyprotein 1abtarget
DB14761RemdesivirRNA-directed RNA polymerase Ltarget
DB14761RemdesivirCytochrome P450 2C8enzyme
DB14761RemdesivirCytochrome P450 2D6enzyme
DB14761RemdesivirCytochrome P450 3A4enzyme
DB14761RemdesivirSolute carrier organic anion transporter family member 1B1transporter
DB14761RemdesivirATP-dependent translocase ABCB1transporter
DB14761RemdesivirSolute carrier organic anion transporter family member 1B3transporter
DB14761RemdesivirBile salt export pumptransporter
DB14761RemdesivirATP-binding cassette sub-family C member 4transporter
DB14761RemdesivirHepatic sodium/bile acid cotransportertransporter
DB14761RemdesivirLiver carboxylesterase 1enzyme
DB14761RemdesivirLysosomal protective proteinenzyme
DB14761RemdesivirReplicase polyprotein 1abtarget
DB14761RemdesivirReplicase polyprotein 1abtarget
DB14761RemdesivirMultidrug and toxin extrusion protein 1transporter
DB00503RitonavirPol polyproteintarget
DB00503RitonavirCytochrome P450 2D6enzyme
DB00503RitonavirCytochrome P450 2C9enzyme
DB00503RitonavirCytochrome P450 2C19enzyme
DB00503RitonavirCytochrome P450 2B6enzyme
DB00503RitonavirCytochrome P450 2C8enzyme
DB00503RitonavirATP-dependent translocase ABCB1transporter
DB00503RitonavirMultidrug resistance-associated protein 1transporter
DB00503RitonavirATP-binding cassette sub-family C member 2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1A2transporter
DB00503RitonavirBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DB00503RitonavirSolute carrier organic anion transporter family member 1B1transporter
DB00503RitonavirCytochrome P450 1A2enzyme
DB00503RitonavirNuclear receptor subfamily 1 group I member 2target
DB00503RitonavirAlbumincarrier
DB00503RitonavirCytochrome P450 3A4enzyme
DB00503RitonavirCytochrome P450 3A5enzyme
DB00503RitonavirCytochrome P450 3A7enzyme
DB00503RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
DB00503RitonavirSolute carrier organic anion transporter family member 2B1transporter
DB00503RitonavirBile salt export pumptransporter
DB00503RitonavirAlpha-1-acid glycoprotein 1carrier
DB00503RitonavirSolute carrier organic anion transporter family member 1B3transporter
DB00503RitonavirGag-Pol polyproteintarget
DrugDrug NamePhaseStatusCount
DB00176Fluvoxamine2Suspended1
DB00051Adalimumab3Withdrawn1