Beta-enolase
Details
- Name
- Beta-enolase
- Synonyms
- 2-phospho-D-glycerate hydro-lyase
- 4.2.1.11
- Enolase 3
- MSE
- Muscle-specific enolase
- Skeletal muscle enolase
- Gene Name
- ENO3
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0009381|Beta-enolase MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK GVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK AIFAGRKFRNPKAK
- Number of residues
- 434
- Molecular Weight
- 46986.485
- Theoretical pI
- Not Available
- GO Classification
- Functionsmagnesium ion binding / phosphopyruvate hydratase activityProcessesaging / canonical glycolysis / carbohydrate metabolic process / gluconeogenesis / glucose metabolic process / response to drug / skeletal muscle tissue regeneration / small molecule metabolic processComponentscytoplasm / cytosol / extracellular exosome / extracellular space / phosphopyruvate hydratase complex / plasma membrane
- General Function
- Phosphopyruvate hydratase activity
- Specific Function
- Appears to have a function in striated muscle development and regeneration.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0017445|Beta-enolase (ENO3) ATGGCCATGCAGAAAATCTTTGCCCGGGAAATCTTGGACTCCAGGGGCAACCCCACGGTG GAGGTGGACCTGCACACGGCCAAGGGCCGATTCCGAGCAGCTGTGCCCAGTGGGGCTTCC ACGGGTATCTATGAGGCTCTGGAACTAAGAGACGGAGACAAAGGCCGCTACCTGGGGAAA GCCAAGTTTGGGGCCAATGCCATCCTGGGCGTGTCCTTGGCCGTGTGTAAGGCGGGAGCA GCTGAGAAGGGGGTCCCCCTGTACCGCCACATCGCAGATCTCGCTGGGAACCCTGACCTC ATACTCCCAGTGCCAGCCTTCAATGTGATCAACGGGGGCTCCCATGCTGGAAACAAGCTG GCCATGCAGGAGTTCATGATTCTGCCTGTGGGAGCCAGCTCCTTCAAGGAAGCCATGCGC ATTGGCGCCGAGGTCTACCACCACCTCAAGGGGGTCATCAAGGCCAAGTATGGGAAGGAT GCCACCAATGTGGGTGATGAAGGTGGCTTCGCACCCAACATCCTGGAGAACAATGAGGCC CTGGAGCTGCTGAAGACGGCCATCCAGGCGGCTGGTTACCCAGACAAGGTGGTGATCGGC ATGGATGTGGCAGCATCTGAGTTCTATCGCAATGGGAAGTACGATCTTGACTTCAAGTCG CCTGATGATCCCGCACGGCACATCACTGGGGAGAAGCTCGGAGAGCTGTATAAGAGCTTT ATCAAGAACTATCCTGTGGTCTCCATCGAAGACCCCTTTGACCAGGATGACTGGGCCACT TGGACCTCCTTCCTCTCGGGGGTGAACATCCAGATTGTGGGGGATGACTTGACAGTCACC AACCCCAAGAGGATTGCCCAGGCCGTTGAGAAGAAGGCCTGCAACTGTCTGCTGCTGAAG GTCAACCAGATCGGCTCGGTGACCGAATCGATCCAGGCGTGCAAACTGGCTCAGTCTAAT GGCTGGGGGGTGATGGTGAGCCACCGCTCTGGGGAGACTGAGGACACATTCATTGCTGAC CTTGTGGTGGGGCTCTGCACAGGACAGATCAAGACTGGCGCCCCCTGCCGCTCGGAGCGT CTGGCCAAATACAACCAACTCATGAGGATCGAGGAGGCTCTTGGGGACAAGGCAATCTTT GCTGGACGCAAGTTCCGTAACCCGAAGGCCAAGTGA
- Chromosome Location
- 17
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P13929 UniProtKB Entry Name ENOB_HUMAN HGNC ID HGNC:3354 - General References
- Peshavaria M, Hinks LJ, Day IN: Structure of human muscle (beta) enolase mRNA and protein deduced from a genomic clone. Nucleic Acids Res. 1989 Nov 11;17(21):8862. [Article]
- Cali L, Feo S, Oliva D, Giallongo A: Nucleotide sequence of a cDNA encoding the human muscle-specific enolase (MSE). Nucleic Acids Res. 1990 Apr 11;18(7):1893. [Article]
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Drug Relations
- Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details DB01819 Phosphoenolpyruvate experimental unknown Details DB01709 2-phospho-D-glyceric acid experimental unknown Details DB03645 Phosphonoacetohydroxamic Acid experimental unknown Details DB02726 2-Phosphoglycolic Acid experimental unknown Details