Enoyl-CoA delta isomerase 1, mitochondrial
Details
- Name
- Enoyl-CoA delta isomerase 1, mitochondrial
- Synonyms
- 3,2-trans-enoyl-CoA isomerase
- 5.3.3.8
- D3,D2-enoyl-CoA isomerase
- DCI
- Delta(3),Delta(2)-enoyl-CoA isomerase
- Dodecenoyl-CoA isomerase
- Gene Name
- ECI1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0003498|Enoyl-CoA delta isomerase 1, mitochondrial MALVASVRVPARVLLRAGARLPGAALGRTERAAGGGDGARRFGSQRVLVEPDAGAGVAVM KFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCGRSPAH YAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQ LGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAI AQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEE KG
- Number of residues
- 302
- Molecular Weight
- 32815.635
- Theoretical pI
- 8.72
- GO Classification
- Functionsdodecenoyl-CoA delta-isomerase activity / intramolecular oxidoreductase activityProcessescellular lipid metabolic process / fatty acid beta-oxidation / small molecule metabolic processComponentsextracellular exosome / mitochondrial inner membrane / mitochondrial matrix / mitochondrion
- General Function
- Intramolecular oxidoreductase activity
- Specific Function
- Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.
- Pfam Domain Function
- ECH_1 (PF00378)
- Transmembrane Regions
- Not Available
- Cellular Location
- Mitochondrion matrix
- Gene sequence
>lcl|BSEQ0011259|Enoyl-CoA delta isomerase 1, mitochondrial (ECI1) ATGGCGCTGGTGGCTTCTGTGCGAGTCCCGGCGCGCGTTCTGCTCCGCGCGGGGGCCCGG CTCCCGGGCGCGGCCCTCGGGCGGACGGAGCGGGCGGCCGGCGGCGGAGACGGCGCGCGG CGCTTCGGGAGCCAGCGGGTGCTGGTGGAGCCGGACGCGGGCGCAGGGGTCGCTGTGATG AAATTCAAGAACCCCCCAGTGAACAGCCTGAGCCTGGAGTTTCTGACGGAGCTGGTCATC AGCCTGGAGAAGCTGGAGAATGACAAGAGCTTCCGCGGTGTCATTCTGACCTCGGACCGC CCGGGTGTCTTCTCGGCCGGCCTGGACCTGACGGAGATGTGTGGGAGGAGCCCCGCCCAC TACGCTGGGTACTGGAAGGCCGTTCAGGAGCTGTGGCTGCGGTTGTACCAGTCCAACCTG GTGCTGGTCTCCGCCATCAACGGAGCCTGCCCCGCTGGAGGCTGCCTGGTGGCCCTGACC TGTGACTACCGCATCCTGGCGGACAACCCCAGGTTGAAAGACACCCTGGAGAACACCATC GGGCACCGGGCGGCGGAGCGTGCCCTGCAGCTGGGGCTGCTCTTCCCGCCGGCGGAGGCC CTGCAGGTGGGCATAGTGGACCAGGTGGTCCCGGAGGAGCAGGTGCAGAGCACTGCGCTG TCAGCGATAGCCCAGTGGATGGCCATTCCAGACCATGCTCGACAGCTGACCAAGGCCATG ATGCGAAAGGCCACGGCCAGCCGCCTGGTCACGCAGCGCGATGCGGACGTGCAGAACTTC GTCAGCTTCATCTCCAAAGACTCCATCCAGAAGTCCCTGCAGATGTACTTAGAGAGGCTC AAAGAAGAAAAAGGCTAA
- Chromosome Location
- 16
- Locus
- 16p13.3
- External Identifiers
Resource Link UniProtKB ID P42126 UniProtKB Entry Name ECI1_HUMAN GenBank Protein ID 472987 GenBank Gene ID Z25820 GenAtlas ID DCI HGNC ID HGNC:2703 - General References
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