Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
Details
- Name
- Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
- Synonyms
- 1.1.1.41
- Isocitric dehydrogenase subunit alpha
- NAD(+)-specific ICDH subunit alpha
- Gene Name
- IDH3A
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0000022|Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR RVKDLD
- Number of residues
- 366
- Molecular Weight
- 39591.365
- Theoretical pI
- 6.93
- GO Classification
- Functionsisocitrate dehydrogenase (NAD+) activity / magnesium ion binding / NAD bindingProcessescarbohydrate metabolic process / cellular metabolic process / small molecule metabolic process / tricarboxylic acid cycleComponentsmitochondrial matrix / mitochondrion / myelin sheath / nucleus
- General Function
- Nad binding
- Specific Function
- Not Available
- Pfam Domain Function
- Iso_dh (PF00180)
- Transmembrane Regions
- Not Available
- Cellular Location
- Mitochondrion
- Gene sequence
>lcl|BSEQ0009871|Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) ATGGCTGGGCCCGCGTGGATCTCTAAGGTCTCTCGGCTGCTGGGGGCATTCCACAACCCA AAACAGGTGACCAGAGGTTTTACTGGTGGTGTTCAGACAGTAACTTTAATTCCAGGAGAT GGTATTGGCCCAGAAATTTCAGCTGCAGTTATGAAGATTTTTGATGCTGCCAAAGCACCT ATTCAGTGGGAGGAGCGGAACGTCACTGCCATTCAAGGACCTGGAGGAAAGTGGATGATC CCTTCAGAGGCTAAAGAGTCCATGGATAAGAACAAGATGGGCTTGAAAGGCCCTTTGAAG ACCCCAATAGCAGCCGGTCACCCATCTATGAATTTACTGCTGCGCAAAACATTTGACCTT TACGCGAATGTCCGACCATGTGTCTCTATCGAAGGCTATAAAACCCCTTACACCGATGTA AATATTGTGACCATTCGAGAGAACACAGAAGGAGAATACAGTGGAATTGAGCATGTGATT GTTGATGGAGTCGTGCAGAGTATCAAGCTCATCACCGAGGGGGCGAGCAAGCGCATTGCT GAGTTTGCCTTTGAGTATGCCCGGAACAACCACCGGAGCAACGTCACGGCGGTGCACAAA GCCAACATCATGCGGATGTCAGATGGGCTTTTTCTACAAAAATGCAGGGAAGTTGCAGAA AGCTGTAAAGATATTAAATTTAATGAGATGTACCTTGATACAGTATGTTTGAATATGGTA CAAGATCCTTCCCAATTTGATGTTCTTGTTATGCCAAATTTGTATGGAGACATCCTTAGT GACTTGTGTGCAGGATTGATCGGAGGTCTCGGTGTGACACCAAGTGGCAACATTGGAGCC AATGGGGTTGCAATTTTTGAGTCGGTTCATGGGACGGCTCCAGACATTGCAGGCAAGGAC ATGGCGAATCCCACAGCCCTCCTGCTCAGTGCCGTGATGATGCTGCGCCACATGGGACTT TTTGACCATGCTGCAAGAATTGAGGCTGCGTGTTTTGCTACAATTAAGGACGGAAAGAGC TTGACAAAAGATTTGGGAGGCAATGCAAAATGCTCAGACTTCACAGAGGAAATCTGTCGC CGAGTAAAAGATTTAGATTAA
- Chromosome Location
- 15
- Locus
- 15q25.1-q25.2
- External Identifiers
Resource Link UniProtKB ID P50213 UniProtKB Entry Name IDH3A_HUMAN GenBank Protein ID 706839 GenBank Gene ID U07681 GenAtlas ID IDH3A HGNC ID HGNC:5384 - General References
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