Gastrotropin
Details
- Name
- Gastrotropin
- Synonyms
- Fatty acid-binding protein 6
- GT
- I-15P
- I-BABP
- ILBP
- Ileal lipid-binding protein
- ILLBP
- Intestinal 15 kDa protein
- Intestinal bile acid-binding protein
- Gene Name
- FABP6
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0003897|Gastrotropin MAFTGKFEMESEKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQHYSGGHTM TNKFTVGKESNIQTMGGKTFKATVQMEGGKLVVNFPNYHQTSEIVGDKLVEVSTIGGVTY ERVSKRLA
- Number of residues
- 128
- Molecular Weight
- 14371.245
- Theoretical pI
- 6.81
- GO Classification
- Functionsbile acid binding / lipid binding / transporter activityProcessesbile acid and bile salt transport / bile acid metabolic process / lipid metabolic process / negative regulation of cell proliferation / small molecule metabolic process / triglyceride catabolic processComponentscytoplasm / cytosol
- General Function
- Transporter activity
- Specific Function
- Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
- Pfam Domain Function
- Lipocalin (PF00061)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0016631|Gastrotropin (FABP6) ATGAAGACAGTGACGATGATGATGGTGGTGGAGATGCAGGCGCTGACTCAGGTTCTGAGA GCTGTGTTGTCTGCGTGCACATGGGTGAGCCGGAAAGGAGACCTGCAGAGAATGAAACAG ACACATAAAGGAAAGCCTCCCAGCAGCATGGCTTTCACCGGCAAGTTCGAGATGGAGAGT GAGAAGAATTATGATGAGTTCATGAAGCTCCTTGGGATCTCCAGCGATGTAATCGAAAAG GCCCGCAACTTCAAGATCGTCACGGAGGTGCAGCAGGATGGGCAGGACTTCACTTGGTCC CAGCACTACTCCGGGGGCCACACCATGACCAACAAGTTCACTGTTGGCAAGGAAAGCAAC ATACAGACAATGGGGGGCAAGACGTTCAAGGCCACTGTGCAGATGGAGGGCGGGAAGCTG GTGGTGAATTTCCCCAACTATCACCAGACCTCAGAGATCGTGGGTGACAAGCTGGTGGAG GTCTCCACCATCGGAGGCGTGACCTATGAGCGCGTGAGCAAGAGACTGGCCTAA
- Chromosome Location
- 5
- Locus
- 5q33.3-q34
- External Identifiers
Resource Link UniProtKB ID P51161 UniProtKB Entry Name FABP6_HUMAN GenBank Protein ID 894183 GenBank Gene ID U19869 GenAtlas ID FABP6 HGNC ID HGNC:3561 - General References
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