NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
Details
- Name
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
- Synonyms
- CI-19kD
- CI-PGIV
- Complex I-19kD
- Complex I-PGIV
- NADH-ubiquinone oxidoreductase 19 kDa subunit
- Gene Name
- NDUFA8
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0010116|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 MPGIVELPTLEELKVDEVKISSAVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEG KLVNKCALDFFRQIKRHCAEPFTEYWTCIDYTGQQLFRHCRKQQAKFDECVLDKLGWVRP DLGELSKVTKVKTDRPLPENPYHSRPRPDPSPEIEGDLQPATHGSRFYFWTK
- Number of residues
- 172
- Molecular Weight
- 20104.875
- Theoretical pI
- 7.74
- GO Classification
- FunctionsNADH dehydrogenase (ubiquinone) activity / protein complex bindingProcessescellular metabolic process / mitochondrial electron transport, NADH to ubiquinone / respiratory electron transport chain / small molecule metabolic processComponentsmitochondrial inner membrane / mitochondrial intermembrane space / mitochondrial respiratory chain complex I / mitochondrion
- General Function
- Protein complex binding
- Specific Function
- Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
- Pfam Domain Function
- CHCH (PF06747)
- Transmembrane Regions
- Not Available
- Cellular Location
- Mitochondrion inner membrane
- Gene sequence
>lcl|BSEQ0010117|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (NDUFA8) ATGCCGGGGATAGTGGAGCTGCCCACTCTAGAGGAGCTGAAAGTAGATGAGGTGAAAATT AGTTCTGCTGTGCTTAAAGCTGCGGCCCATCACTATGGAGCTCAATGTGATAAGCCCAAC AAGGAGTTTATGCTCTGCCGCTGGGAAGAGAAAGATCCGAGGCGGTGTTTAGAGGAAGGC AAACTGGTCAACAAGTGTGCTTTGGACTTCTTTAGGCAGATAAAACGTCACTGTGCAGAG CCTTTTACAGAATATTGGACTTGCATTGATTATACTGGCCAGCAGTTATTTCGTCACTGT CGCAAACAGCAGGCAAAGTTTGACGAGTGTGTGCTGGACAAACTGGGCTGGGTGCGGCCT GACCTGGGAGAACTGTCAAAGGTCACCAAAGTGAAAACAGATCGACCTTTACCGGAGAAT CCCTATCACTCAAGACCAAGACCGGATCCCAGCCCTGAGATCGAGGGAGATCTGCAGCCT GCCACACATGGCAGCCGCTTTTATTTCTGGACCAAGTAA
- Chromosome Location
- 9
- Locus
- 9q33.2-q34.11
- External Identifiers
Resource Link UniProtKB ID P51970 UniProtKB Entry Name NDUA8_HUMAN GenBank Protein ID 5326825 GenBank Gene ID AF044953 GenAtlas ID NDUFA8 HGNC ID HGNC:7692 - General References
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