Mitochondrial potassium channel
Details
- Name
- Mitochondrial potassium channel
- Synonyms
- Coiled-coil domain-containing protein 51
- MITOK
- Gene Name
- CCDC51
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0052469|Mitochondrial potassium channel MMGRSPGFAMQHIVGVPHVLVRRGLLGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHRL PALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAR EDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFS LFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKG PVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLS AALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSF LLEQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVTFVATLPVLYMLFKAS
- Number of residues
- 411
- Molecular Weight
- 45810.91
- Theoretical pI
- Not Available
- GO Classification
- Functionsmitochondrial ATP-gated potassium channel activityProcessespotassium ion transmembrane transportComponentsintegral component of mitochondrial inner membrane / mitochondrial ATP-gated potassium channel complex
- General Function
- Mitochondrial potassium channel located in the mitochondrial inner membrane (PubMed:31435016). Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (PubMed:31435016). May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume (PubMed:31435016).
- Specific Function
- Mitochondrial atp-gated potassium channel activity
- Pfam Domain Function
- Not Available
- Transmembrane Regions
- 202-222 387-407
- Cellular Location
- Mitochondrion inner membrane
- Gene sequence
>lcl|BSEQ0052470|Mitochondrial potassium channel (CCDC51) ATGATGGGGCGCAGCCCTGGGTTTGCCATGCAGCACATCGTGGGTGTGCCCCACGTACTG GTTCGGAGGGGCCTCCTTGGAAGGGACCTCTTCATGACCAGGACTCTCTGCAGCCCAGGC CCAAGCCAGCCCGGAGAGAAAAGACCTGAGGAGGTGGCCCTGGGGCTGCACCACCGCCTC CCAGCACTGGGAAGAGCCCTGGGGCACAGCATTCAGCAACGAGCGACCTCCACAGCCAAG ACTTGGTGGGACAGATATGAAGAGTTTGTTGGACTCAACGAGGTTCGAGAGGCCCAGGGA AAGGTGACAGAGGCTGAGAAAGTGTTCATGGTGGCTCGAGGGCTTGTCCGAGAGGCTCGG GAGGACTTGGAAGTTCACCAGGCCAAGCTGAAGGAGGTGAGGGACCGCTTGGACCGTGTC TCCAGGGAGGACAGTCAGTACTTGGAACTGGCTACTCTCGAGCACAGGATGCTGCAGGAG GAGAAGAGGCTTCGCACAGCCTATCTGCGTGCAGAAGACTCTGAGCGAGAGAAGTTCTCC CTCTTCTCTGCAGCTGTGCGGGAAAGTCATGAGAAGGAGCGCACAAGGGCTGAGAGGACC AAGAACTGGTCCCTCATTGGCTCAGTCCTGGGGGCCCTGATTGGTGTGGCTGGCTCCACC TATGTGAACCGTGTGCGACTACAGGAGCTGAAGGCTTTACTCCTGGAGGCGCAGAAGGGG CCTGTGAGTCTCCAAGAGGCCATTCGAGAACAGGCGTCTAGCTACTCCCGCCAGCAGAGG GACCTCCACAATCTCATGGTGGACCTGAGGGGCCTGGTACATGCTGCTGGGCCAGGGCAG GACTCTGGGTCACAGGCAGGTAGTCCCCCGACCAGAGACAGAGATGTAGATGTCCTTTCA GCTGCCTTGAAAGAGCAGCTTAGTCATTCCAGGCAAGTCCATTCATGTCTAGAAGGCTTA CGAGAGCAGCTTGATGGCCTAGAAAAGACTTGTAGCCAAATGGCTGGGGTGGTTCAGCTT GTAAAGTCTGCAGCACACCCAGGCCTGGTGGAACCAGCAGACGGGGCTATGCCCAGCTTC TTGCTGGAGCAGGGGAGCATGATCTTGGCACTGTCAGACACGGAGCAGAGACTAGAAGCC CAAGTCAACAGGAACACCATCTATAGCACCCTGGTCACCTGTGTGACATTTGTGGCCACA CTGCCTGTGCTCTACATGCTATTCAAAGCCAGCTAA
- Chromosome Location
- 3
- Locus
- 3p21.31
- External Identifiers
Resource Link UniProtKB ID Q96ER9 UniProtKB Entry Name MITOK_HUMAN HGNC ID HGNC:25714 - General References
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