Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial
Details
- Name
- Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial
- Synonyms
- 2.5.1.17
- Cob(I)alamin adenosyltransferase
- Methylmalonic aciduria type B protein
- Gene Name
- MMAB
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0018952|Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial MAVCGLGSRLGLGSRLGLRGCFGAARLLYPRFQSRGPQGVEDGDRPQPSSKTPRIPKIYT KTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCT LQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISS ALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK NDPSAESEGL
- Number of residues
- 250
- Molecular Weight
- 27387.975
- Theoretical pI
- 8.78
- GO Classification
- FunctionsATP binding / cob(I)yrinic acid a,c-diamide adenosyltransferase activityProcessescobalamin biosynthetic process / cobalamin metabolic process / small molecule metabolic process / vitamin metabolic process / water-soluble vitamin metabolic processComponentsmitochondrial matrix
- General Function
- Cob(i)yrinic acid a,c-diamide adenosyltransferase activity
- Specific Function
- Not Available
- Pfam Domain Function
- Cob_adeno_trans (PF01923)
- Transmembrane Regions
- Not Available
- Cellular Location
- Mitochondrion
- Gene sequence
>lcl|BSEQ0018953|Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial (MMAB) ATGGCTGTGTGCGGCCTGGGGAGCCGTCTTGGCCTGGGGAGCCGTCTTGGCCTGCGCGGG TGCTTCGGCGCCGCCAGGCTCCTGTATCCCCGTTTCCAGAGCCGCGGCCCTCAGGGCGTG GAAGACGGGGACAGGCCACAGCCTTCCTCGAAGACACCCAGGATCCCCAAGATTTACACC AAAACGGGAGACAAAGGGTTTTCTAGTACCTTCACAGGAGAAAGGAGACCCAAAGATGAC CAAGTGTTTGAAGCCGTGGGAACTACAGATGAATTAAGTTCAGCTATTGGGTTTGCTCTG GAATTAGTCACAGAAAAGGGCCATACATTTGCCGAAGAGCTTCAGAAAATCCAGTGCACA TTGCAGGACGTCGGCTCGGCCCTGGCGACACCATGCTCCTCGGCCCGGGAGGCTCACTTA AAGTATACCACGTTCAAGGCGGGGCCCATCCTGGAGCTGGAGCAGTGGATCGACAAGTAC ACCAGCCAGCTCCCACCACTCACGGCCTTCATCCTGCCTTCGGGAGGCAAGATCAGCTCG GCGCTGCATTTCTGCCGGGCCGTGTGCCGCCGGGCCGAGAGACGTGTGGTGCCTCTTGTC CAGATGGGAGAGACCGATGCGAACGTGGCCAAGTTCTTAAACAGACTCAGTGACTATCTC TTCACGCTAGCCAGATATGCAGCCATGAAGGAGGGGAATCAAGAGAAAATATACATGAAA AATGACCCATCGGCCGAGTCTGAGGGACTCTGA
- Chromosome Location
- 12
- Locus
- 12q24
- External Identifiers
Resource Link UniProtKB ID Q96EY8 UniProtKB Entry Name MMAB_HUMAN GenBank Protein ID 26284726 GenBank Gene ID AF550404 GenAtlas ID MMAB HGNC ID HGNC:19331 - General References
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- Leal NA, Park SD, Kima PE, Bobik TA: Identification of the human and bovine ATP:Cob(I)alamin adenosyltransferase cDNAs based on complementation of a bacterial mutant. J Biol Chem. 2003 Mar 14;278(11):9227-34. Epub 2003 Jan 3. [Article]
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