Solute carrier family 52, riboflavin transporter, member 2
Details
- Name
- Solute carrier family 52, riboflavin transporter, member 2
- Synonyms
- GPR172A
- hRFT3
- PAR1
- PERV-A receptor 1
- Porcine endogenous retrovirus A receptor 1
- Protein GPR172A
- RFT3
- Riboflavin transporter 3
- Gene Name
- SLC52A2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0013324|Solute carrier family 52, riboflavin transporter, member 2 MAAPTPARPVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSYVSVLVALGNL GLLVVTLWRRLAPGKDEQVPIRVVQVLGMVGTALLASLWHHVAPVAGQLHSVAFLALAFV LALACCASNVTFLPFLSHLPPRFLRSFFLGQGLSALLPCVLALVQGVGRLECPPAPINGT PGPPLDFLERFPASTFFWALTALLVASAAAFQGLLLLLPPPPSVPTGELGSGLQVGAPGA EEEVEESSPLQEPPSQAAGTTPGPDPKAYQLLSARSACLLGLLAATNALTNGVLPAVQSF SCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLGGLSLLGVFCGGYLMALAVLS PCPPLVGTSAGVVLVVLSWVLCLGVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGA VAMFPPTSIYHVFHSRKDCADPCDS
- Number of residues
- 445
- Molecular Weight
- 45776.61
- Theoretical pI
- Not Available
- GO Classification
- Functionsriboflavin transporter activity / virus receptor activityProcessesriboflavin transportComponentsintegral component of plasma membrane
- General Function
- Virus receptor activity
- Specific Function
- Riboflavin transporter. Riboflavin transport is Na(+)-independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin. Weakly inhibited by flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN). In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).
- Pfam Domain Function
- DUF1011 (PF06237)
- Transmembrane Regions
- 14-34 47-67 86-106 112-132 147-167 196-216 277-297 312-332 339-359 366-386 404-424
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0013325|Solute carrier family 52, riboflavin transporter, member 2 (SLC52A2) ATGGCAGCACCCACGCCCGCCCGTCCGGTGCTGACCCACCTGCTGGTGGCTCTCTTCGGC ATGGGCTCCTGGGCTGCGGTCAATGGGATCTGGGTGGAGCTACCTGTGGTGGTCAAAGAG CTTCCAGAGGGTTGGAGCCTCCCCTCTTACGTCTCTGTGCTTGTGGCTCTGGGGAACCTG GGTCTGCTGGTGGTGACCCTCTGGAGGAGGCTGGCCCCAGGAAAGGACGAGCAGGTCCCC ATCCGGGTGGTGCAGGTGCTGGGCATGGTGGGCACAGCCCTGCTGGCCTCTCTGTGGCAC CATGTGGCCCCAGTGGCAGGACAGTTGCATTCTGTGGCCTTCTTAGCACTGGCCTTTGTG CTGGCACTGGCATGCTGTGCCTCGAATGTCACTTTCCTGCCCTTCTTGAGCCACCTGCCA CCTCGCTTCTTACGGTCATTCTTCCTGGGTCAAGGCCTGAGTGCCCTGCTGCCCTGCGTG CTGGCCCTAGTGCAGGGTGTGGGCCGCCTCGAGTGCCCGCCAGCCCCCATCAACGGCACC CCTGGCCCCCCGCTCGACTTCCTTGAGCGTTTTCCCGCCAGCACCTTCTTCTGGGCACTG ACTGCCCTTCTGGTCGCTTCAGCTGCTGCCTTCCAGGGTCTTCTGCTGCTGTTGCCGCCA CCACCATCTGTACCCACAGGGGAGTTAGGATCAGGCCTCCAGGTGGGAGCCCCAGGAGCA GAGGAAGAGGTGGAAGAGTCCTCACCACTGCAAGAGCCACCAAGCCAGGCAGCAGGCACC ACCCCTGGTCCAGACCCTAAGGCCTATCAGCTTCTATCAGCCCGCAGTGCCTGCCTGCTG GGCCTGTTGGCCGCCACCAACGCGCTGACCAATGGCGTGCTGCCTGCCGTGCAGAGCTTT TCCTGCTTACCCTACGGGCGTCTGGCCTACCACCTGGCTGTGGTGCTGGGCAGTGCTGCC AATCCCCTGGCCTGCTTCCTGGCCATGGGTGTGCTGTGCAGGTCCTTGGCAGGGCTGGGC GGCCTCTCTCTGCTGGGCGTGTTCTGTGGGGGCTACCTGATGGCGCTGGCAGTCCTGAGC CCCTGCCCGCCCCTGGTGGGCACCTCGGCGGGGGTGGTCCTCGTGGTGCTGTCGTGGGTG CTGTGTCTTGGCGTGTTCTCCTACGTGAAGGTGGCAGCCAGCTCCCTGCTGCATGGCGGG GGCCGGCCGGCATTGCTGGCAGCCGGCGTGGCCATCCAGGTGGGCTCTCTGCTCGGCGCT GTTGCTATGTTCCCCCCGACCAGCATCTATCACGTGTTCCACAGCAGAAAGGACTGTGCA GACCCCTGTGACTCCTGA
- Chromosome Location
- 8
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9HAB3 UniProtKB Entry Name S52A2_HUMAN HGNC ID HGNC:30224 - General References
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