[Treatment of periodontal disease, prevention and bisphosphonate].

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Takaishi Y

[Treatment of periodontal disease, prevention and bisphosphonate].

Clin Calcium. 2003 Feb;13(2):173-6.

PubMed ID

15775080 [ View in PubMed

]

Abstract

The bisphosphonate has a high affinity in the hydroxyapatite which is the main constituent of the bone and remarkably suppresses the bone resorption. Thus bisphosphonate administer inhibits the resorption of the alveolar bone and the jaw bone with periodontitis, and there is a possibility of contributing to the treatment of the periodontitis. Then, the etidronate was prescribed for four patients periodontitis for 2-3 years according to the usual dose of the osteoporosis in addition to dental treatment, and the clinical course was followed. It is considered that etidronate controls the resorption of the alveolar bone for 2-3 years, maintains structure and function of the gums and the periodontal tissue, and is useful as the remedy of chronic periodontitis.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Etidronic acid	Hydroxylapatite	Small molecule	Humans	Yes	Antagonist	Details