Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.

Article Details

Citation

Guan Y, Zheng BJ, He YQ, Liu XL, Zhuang ZX, Cheung CL, Luo SW, Li PH, Zhang LJ, Guan YJ, Butt KM, Wong KL, Chan KW, Lim W, Shortridge KF, Yuen KY, Peiris JS, Poon LL

Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China.

Science. 2003 Oct 10;302(5643):276-8. Epub 2003 Sep 4.

PubMed ID
12958366 [ View in PubMed
]
Abstract

A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working at the same market. All the animal isolates retain a 29-nucleotide sequence that is not found in most human isolates. The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Replicase polyprotein 1abP0C6X7Details
Replicase polyprotein 1aP0C6U8Details