Calmodulin-dependent protein kinase IV: regulation of function and expression.
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Krebs J
Calmodulin-dependent protein kinase IV: regulation of function and expression.
Biochim Biophys Acta. 1998 Dec 10;1448(2):183-9.
- PubMed ID
- 9920409 [ View in PubMed]
- Abstract
Calmodulin-dependent protein kinase IV (CaMKIV) is a key mediator of Ca2+-induced gene expression. This serine/threonine kinase is itself activated by a calmodulin kinase kinase. In the present contribution the gene structure, regulation of activity, the role in Ca2+-dependent gene expression, and the hormonal induction and controlled expression of CaMKIV during tissue development are reviewed.