Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation.

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Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW

Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation.

Angew Chem Int Ed Engl. 2012 Jun 18;51(25):6140-3. doi: 10.1002/anie.201201358. Epub 2012 May 8.

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22566140 [ View in PubMed
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DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
GTPase KRasP01116Details