Identification of a new allele, HLA-DRB5*0113, through three different molecular biology techniques.
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Garino E, Berrino M, Bertinetto F, Caropreso P, Chidichimo R, Dametto E, Fasano ME, Frisaldi E, Mazzola G, Tondat F, Boccadoro M, Bruno B, Amoroso A
Identification of a new allele, HLA-DRB5*0113, through three different molecular biology techniques.
Tissue Antigens. 2006 May;67(5):427-9.
- PubMed ID
- 16671952 [ View in PubMed]
- Abstract
A new HLA-DRB5 allele, HLA-DRB5*0113, has been identified in an Italian patient during routine HLA typing in order to activate a bone marrow donor search. HLA typing was performed by different molecular biology techniques, and the results showed that the HLA-DRB5*0113 allele differs from HLA-DRB5*010101 allele for three nucleotide substitutions at codons 57 (GAC-->GAT; Asp) and 58 (GCT-->GAG; Ala-->Glu) of exon 2.