Cloning and molecular analysis of the human citrate synthase gene.
Article Details
- CitationCopy to clipboard
Goldenthal MJ, Marin-Garcia J, Ananthakrishnan R
Cloning and molecular analysis of the human citrate synthase gene.
Genome. 1998 Oct;41(5):733-8.
- PubMed ID
- 9809442 [ View in PubMed]
- Abstract
The nucleotide sequence encoding the citrate synthase (CS) gene was determined from the sequencing of the CS cDNA isolated from a human heart cDNA library. The primary sequence of CS deduced from its nucleotide sequence reveals a highly conserved, albeit slightly larger, protein of 466 amino acids, with 95% homology to its pig homologue. The data also indicate that the human genomic CS gene contains no introns, and confirms the location of the human CS gene on chromosome 12.