Basiliximab interferes with the detection of soluble IL-2 receptor by the Immulite Immunoassay system.

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Warle MC, Kwekkeboom J, Tilanus HW, Metselaar HJ

Basiliximab interferes with the detection of soluble IL-2 receptor by the Immulite Immunoassay system.

J Immunol Methods. 2003 Apr 1;275(1-2):133-6.

PubMed ID

12667677 [ View in PubMed

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Abstract

The use of the Immulite Automated Immunoassay system is becoming an increasingly popular method for accurate and fast measurement of sIL-2R in serum. Here, we report that detection of sIL-2R using the Immulite Immunoassay system in serum samples of patients who are treated with basiliximab, a monoclonal antibody against the alpha-chain of the IL-2 receptor, may lead to false measurements.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Basiliximab	Interleukin-2 receptor subunit beta	Protein	Humans	Unknown	Antibody	Details