TMEM16A protein: a new identity for Ca(2+)-dependent Cl(-) channels.

Article Details

Citation

Ferrera L, Caputo A, Galietta LJ

TMEM16A protein: a new identity for Ca(2+)-dependent Cl(-) channels.

Physiology (Bethesda). 2010 Dec;25(6):357-63. doi: 10.1152/physiol.00030.2010.

PubMed ID
21186280 [ View in PubMed
]
Abstract

Ca(+)-dependent Cl(-) channels (CaCCs) play a variety of physiological roles in different organs and tissues, including transepithelial Cl(-) secretion, smooth muscle contraction, regulation of neuronal excitability, and transduction of sensory stimuli. The recent identification of TMEM16A protein as an important component of CaCCs should allow a better understanding of their physiological role, structure-function relationship, and regulatory mechanisms.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Anoctamin-1Q5XXA6Details