Family of human Na+,K+-ATPase genes. Structure of the putative regulatory region of the alpha+-gene.
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Sverdlov ED, Bessarab DA, Malyshev IV, Petrukhin KE, Smirnov YuV, Ushkaryov YuA, Monastyrskaya GS, Broude NE, Modyanov NN
Family of human Na+,K+-ATPase genes. Structure of the putative regulatory region of the alpha+-gene.
FEBS Lett. 1989 Feb 27;244(2):481-3.
- PubMed ID
- 2537767 [ View in PubMed]
- Abstract
The primary structure of the putative regulatory region of a gene of the Na+,K+-ATPase multigene family in the human genome has been determined. This region includes the first exon with all of the untranslatable sequence of mRNA and a dozen nucleotides, coding for the first four amino acids of the hypothetic precursor of the alpha+-subunit. The entire region comprises over 1400 bp. The possible role of specific nucleotide blocks within this region in comparison with other genes is discussed.