Bone mineralization in newborns whose mothers received magnesium sulphate for tocolysis of premature labour.

Article Details

Citation
Copy to clipboard

Malaeb SN, Rassi AI, Haddad MC, Seoud MA, Yunis KA

Bone mineralization in newborns whose mothers received magnesium sulphate for tocolysis of premature labour.

Pediatr Radiol. 2004 May;34(5):384-6. Epub 2004 Feb 18.

PubMed ID
14985884 [ View in PubMed
]
Abstract

Prolonged maternal magnesium sulphate infusion therapy for tocolysis of premature labour may result in secondary fetal hypermagnesaemia, which has been associated with bony abnormalities in the newborn. We report on four infants, members of two twin pregnancies, who were exposed to prolonged fetal hypermagnesaemia. Three of the infants, all appropriate for gestational age, showed abnormal radiological findings consisting of abnormal mineralisation of long-bone metaphyses owing to fetal hypermagnesaemia. The fourth infant, who was growth retarded, had normal bones. Intrauterine growth restriction appears to be protective against magnesium sulphate-induced abnormal bone mineralisation in the newborn.

DrugBank Data that Cites this Article

Drugs