Effect of 0.5% apraclonidine on ptosis in Horner syndrome.

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Garibaldi DC, Hindman HB, Grant MP, Iliff NT, Merbs SL

Effect of 0.5% apraclonidine on ptosis in Horner syndrome.

Ophthal Plast Reconstr Surg. 2006 Jan-Feb;22(1):53-5.

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16418668 [ View in PubMed
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Abstract

To demonstrate the effect of apraclonidine on anisocoria and ptosis in Horner syndrome, one drop of 0.5% apraclonidine was instilled in both eyes of 3 patients who presented with acute Horner syndrome, and the effect on ptosis and anisocoria was documented. As reported in the literature, one drop of 0.5% apraclonidine reverses the anisocoria of Horner syndrome. In addition, 0.5% apraclonidine leads to a complete resolution of the ptosis associated with Horner syndrome, a finding reported once in the literature. Apraclonidine is a safe and readily available alternative to cocaine for the diagnosis of Horner syndrome.

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