Pharmacological, therapeutic and toxicological properties of furazolidone: some recent research.

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Ali BH

Pharmacological, therapeutic and toxicological properties of furazolidone: some recent research.

Vet Res Commun. 1999 Oct;23(6):343-60.

PubMed ID

10543364 [ View in PubMed

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Abstract

Some of the recent publications on the pharmacological, therapeutic and toxicological properties of the antimicrobial agent furazolidone (FZ) are briefly reviewed. In animals, most of the recently published papers focus on (1) the methodology of measuring the residues of the drug and its metabolites in edible tissues; (2) the carcinogenicity and genotoxicity of FZ; (3) the cellular and molecular basis of FZ-induced cardiomyopthy, and the action of different cardioprotectant drugs thereon; and (4) hormonal effects. In humans, the use of FZ as an anti-ulcer drug and in controlling infectious diseases, especially opportunistic infections in AIDS patients, is described.

DrugBank Data that Cites this Article

Drug Enzymes

Drug	Enzyme	Kind	Organism	Pharmacological Action	Actions
Furazolidone	Amine oxidase [flavin-containing] A	Protein	Humans	Unknown	Inhibitor	Details
Furazolidone	Amine oxidase [flavin-containing] B	Protein	Humans	Unknown	Inhibitor	Details