Penetration resistance: PKR's other talent.

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Lacy-Hulbert A, Stuart LM

Penetration resistance: PKR's other talent.

Immunity. 2012 May 25;36(5):695-6. doi: 10.1016/j.immuni.2012.05.010.

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22633454 [ View in PubMed

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Abstract

In this issue of Immunity, Irving et al. (2012) show that protein kinase R (PKR) regulates the cytoskeleton via an interaction with gelsolin. This alternative role for PKR prevents penetration of virions into the cell.

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Polypeptides

Name	UniProt ID
Interferon-induced, double-stranded RNA-activated protein kinase	P19525	Details