The identification and subcellular localization of human MRK.
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Yang T, Jiang Y, Chen J
The identification and subcellular localization of human MRK.
Biomol Eng. 2002 Jun;19(1):1-4.
- PubMed ID
- 12103360 [ View in PubMed]
- Abstract
A novel human kinase gene, human MRK (hMRK), was cloned by using degenerate RT-PCR. The hMRK encoded a putative 632 amino acids protein and was highly homologous to rat MRK (rMRK) in the entire coding region. The hMRK was located at chromosome 6p12.3 by RH-PCR analysis. The hMRK was generally expressed a single approximately 6.3 kb transcript at a low level in a variety of tissues except at a high level in testis. The full-length hMRK protein was fused to C-terminal of GFP and expressed in Hela cells. The fluorescence microscopy results identified its nuclear localization.