Isolation, structure, and synthesis of a human seminal plasma peptide with inhibin-like activity.
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Ramasharma K, Sairam MR, Seidah NG, Chretien M, Manjunath P, Schiller PW, Yamashiro D, Li CH
Isolation, structure, and synthesis of a human seminal plasma peptide with inhibin-like activity.
Science. 1984 Mar 16;223(4641):1199-202.
- PubMed ID
- 6422553 [ View in PubMed]
- Abstract
A basic peptide isolated from pooled human seminal plasma exhibited inhibin-like activity by suppressing pituitary follicle-stimulating hormone secretion in vitro and in vivo. The peptide has been characterized and sequenced, and a 31-amino-acid synthetic replicate showed full biological activity in vitro.