Evidence for a signal peptide at the amino-terminal end of human mitochondrial aldehyde dehydrogenase.
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Braun T, Bober E, Singh S, Agarwal DP, Goedde HW
Evidence for a signal peptide at the amino-terminal end of human mitochondrial aldehyde dehydrogenase.
FEBS Lett. 1987 May 11;215(2):233-6.
- PubMed ID
- 3582651 [ View in PubMed]
- Abstract
A full-length cDNA clone coding for human mitochondrial aldehyde dehydrogenase (ALDH I) was isolated from a human fetal muscle cDNA library. Sequence analysis revealed structural similarities between the amino-terminal end of ALDH I and other known targeting sequences responsible for protein uptake into the mitochondria.