Human N-methyl-D-aspartate receptor modulatory subunit hNR2A: cloning and sequencing of the cDNA and primary structure of the protein.

Article Details

Citation

Foldes RL, Adams SL, Fantaske RP, Kamboj RK

Human N-methyl-D-aspartate receptor modulatory subunit hNR2A: cloning and sequencing of the cDNA and primary structure of the protein.

Biochim Biophys Acta. 1994 Aug 11;1223(1):155-9.

PubMed ID
8061049 [ View in PubMed
]
Abstract

Several cDNA clones encoding the human N-methyl-D-aspartate receptor modulatory subunit hNR2A, were isolated from human hippocampus and fetal brain libraries. DNA sequence analysis revealed overlapping clones permitting the reconstruction of full-length hNR2A cDNA. The hNR2A cDNA demonstrated an 88-89% nucleotide (nt) identity with the corresponding rodent cDNAs. The nt sequence of hNR2A would encode a 1464-aa protein that has a 95.2% identity with the rodent NR2A subunits.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Glutamate receptor ionotropic, NMDA 2AQ12879Details