Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool.

Article Details

Citation

Zong Z, Partridge SR, Thomas L, Iredell JR

Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool.

Antimicrob Agents Chemother. 2008 Nov;52(11):4198-202. doi: 10.1128/AAC.00107-08. Epub 2008 Aug 25.

PubMed ID
18725449 [ View in PubMed
]
Abstract

bla(CTX-M) genes, particularly bla(CTX-M-15), are the dominant extended-spectrum beta-lactamase (ESBL) genes among clinical isolates of Escherichia coli and Klebsiella pneumoniae in Sydney, Australia, where we also found one example of bla(CTX-M-62), encoding a novel enzyme conferring ceftazidime resistance. ESBL genes were present in diverse community isolates and in a variety of associated conjugative plasmids.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Beta-lactamaseQ9L5C7Details
Beta-lactamaseQ840M4Details