Thermolabile phenol sulfotransferase gene (STM): localization to human chromosome 16p11.2.

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Citation

Aksoy IA, Callen DF, Apostolou S, Her C, Weinshilboum RM

Thermolabile phenol sulfotransferase gene (STM): localization to human chromosome 16p11.2.

Genomics. 1994 Sep 1;23(1):275-7.

PubMed ID
7829089 [ View in PubMed
]
Abstract

Thermolabile (TL) phenol sulfotransferase (PST) catalyzes the sulfate conjugation of phenolic monoamine neurotransmitters such as dopamine and serotonin. We recently cloned a cDNA for human liver TL PST and expressed it in COS-1 cells. We now report the chromosomal localization of the human TL PST gene (STM) as well as its partial sequence. DNA from NIGMS Human/Rodent Somatic Cell Hybrid Mapping Panels 1 and 2 was screened by use of the PCR, and the STM gene was mapped to chromosome 16. Regional localization to 16p11.2 was performed by PCR analysis of a high-resolution mouse/human somatic cell hybrid panel that contained defined portions of human chromosome 16.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Sulfotransferase 1A3P0DMM9Details