A comparison of antrafenine and aspirin on platelet aggregation and frusemide-induced diuresis.

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Hassan SM, Olivesi A, Fish A, Turner P

A comparison of antrafenine and aspirin on platelet aggregation and frusemide-induced diuresis.

Postgrad Med J. 1982 Jan;58(675):17-9.

PubMed ID

7088753 [ View in PubMed

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Abstract

The effects of antrafenine were compared with aspirin and placebo on platelet aggregation and on the diuretic action of frusemide in normal volunteers. Aspirin significantly reduced platelet aggregation at 3 and 6 hr after administration, but antrafenine only at 3 hr. Only aspirin significantly reduced the increase in urine sodium and potassium produced by frusemide.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Antrafenine	Prostaglandin G/H synthase 1	Protein	Humans	Unknown	Inhibitor	Details