Mechanisms by which diabetes increases cardiovascular disease.

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Gleissner CA, Galkina E, Nadler JL, Ley K

Mechanisms by which diabetes increases cardiovascular disease.

Drug Discov Today Dis Mech. 2007;4(3):131-140. doi: 10.1016/j.ddmec.2007.12.005.

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18695749 [ View in PubMed
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Abstract

Diabetes mellitus is one of the major risk factors for cardiovascular disease which is the leading cause of death in the U.S. Increasing prevalence of diabetes and diabetic atherosclerosis makes identification of molecular mechanisms by which diabetes promotes atherogenesis an important task. Targeting common pathways may ameliorate both diseases. This review focuses on well known as well as newly discovered mechanisms which may represent promising therapeutic targets.

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