Tibia vara caused by focal fibrocartilaginous dysplasia. Three case reports.

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Bell SN, Campbell PE, Cole WG, Menelaus MB

Tibia vara caused by focal fibrocartilaginous dysplasia. Three case reports.

J Bone Joint Surg Br. 1985 Nov;67(5):780-4.

PubMed ID

4055881 [ View in PubMed

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Abstract

We present three cases of a previously undescribed condition characterised by unilateral tibia vara associated with an area of focal fibrocartilaginous dysplasia in the medial aspect of the proximal tibia. The three children affected were aged 9, 15 and 27 months respectively. Two required tibial osteotomy, but in one the deformity resolved without treatment. The pathogenesis of the focal lesion remains conjectural; the most likely explanation is that the mesenchymal anlage of the tibial metaphysis has, for unknown reasons, developed abnormally at the insertion of the pes anserinus.

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Drug	Target	Kind	Organism	Pharmacological Action	Actions
Mirtazapine	5HT3 serotonin receptor	Protein	Humans	Yes	Antagonist	Details