PharmGKB summary: mycophenolic acid pathway.

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Lamba V, Sangkuhl K, Sanghavi K, Fish A, Altman RB, Klein TE

PharmGKB summary: mycophenolic acid pathway.

Pharmacogenet Genomics. 2014 Jan;24(1):73-9. doi: 10.1097/FPC.0000000000000010.

PubMed ID

24220207 [ View in PubMed

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Abstract

Not Available

DrugBank Data that Cites this Article

Drugs

Mycophenolate mofetil

Drug Enzymes

Drug	Enzyme	Kind	Organism	Pharmacological Action	Actions
Mycophenolate mofetil	Carboxylic ester hydrolase	Protein	Humans	Unknown	Substrate	Details
Mycophenolate mofetil	Cytochrome P450 2C8	Protein	Humans	Unknown	Substrate	Details
Mycophenolate mofetil	Cytochrome P450 3A4	Protein	Humans	Unknown	Substrate	Details
Mycophenolate mofetil	Cytochrome P450 3A5	Protein	Humans	Unknown	Substrate	Details
Mycophenolate mofetil	Liver carboxylesterase 1	Protein	Humans	Unknown	Substrate	Details
Mycophenolate mofetil	UDP-glucuronosyltransferase 1-7	Protein	Humans	Unknown	Substrate	Details
Mycophenolate mofetil	UDP-glucuronosyltransferase 1-8	Protein	Humans	Unknown	Substrate	Details
Mycophenolate mofetil	UDP-glucuronosyltransferase 2B7	Protein	Humans	Unknown	Substrate	Details

Drug Transporters

Drug	Transporter	Kind	Organism	Pharmacological Action	Actions
Mycophenolate mofetil	Solute carrier organic anion transporter family member 1B1	Protein	Humans	Unknown	Substrate	Details
Mycophenolate mofetil	Solute carrier organic anion transporter family member 1B3	Protein	Humans	Unknown	Substrate	Details

Drug Reactions

Reaction
Mycophenolate mofetil DB00688 Liver carboxylesterase 1 Carboxylic ester hydrolase Mycophenolic acid DB01024	Details
Mycophenolate mofetil DB00688 UDP-glucuronosyltransferase 1-9 UDP-glucuronosyltransferase 1-1 UDP-glucuronosyltransferase 1-8 UDP-glucuronosyltransferase 1-7 UDP-glucuronosyltransferase 1-10 Mycophenolic acid glucuronide DBMET00916 Mycophenolic acyl-glucuronide (AcMPAG) DBMET02607	Details
Mycophenolate mofetil DB00688 Carboxylic ester hydrolase N-(2-carboxymethyl)-morpholine DBMET00918	Details
Mycophenolate mofetil DB00688 Carboxylic ester hydrolase N-(2-hydroxyethyl)-morpholine DBMET00919	Details
Mycophenolate mofetil DB00688 Carboxylic ester hydrolase N-(2-hydroxyethyl)-morpholine N-oxide DBMET00920	Details

Drug Interactions

• Approved
• Vet approved
• Nutraceutical
• Illicit
• Withdrawn
• Investigational
• Experimental
• All Drugs

Drugs	Interaction
Integrate drug-drug interactions in your software
Cyproterone acetate Mycophenolate mofetil	The serum concentration of Cyproterone acetate can be decreased when it is combined with Mycophenolate mofetil.
Cyproterone acetate Mycophenolic acid	The serum concentration of Cyproterone acetate can be decreased when it is combined with Mycophenolic acid.
Desogestrel Mycophenolate mofetil	The serum concentration of Desogestrel can be decreased when it is combined with Mycophenolate mofetil.
Desogestrel Mycophenolic acid	The serum concentration of Desogestrel can be decreased when it is combined with Mycophenolic acid.
Dienogest Mycophenolate mofetil	The serum concentration of Dienogest can be decreased when it is combined with Mycophenolate mofetil.