Nadolol binding to human serum proteins.

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Patel L, Johnson A, Turner P

Nadolol binding to human serum proteins.

J Pharm Pharmacol. 1984 Jun;36(6):414-5. doi: 10.1111/j.2042-7158.1984.tb04413.x.

PubMed ID
6146679 [ View in PubMed
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Abstract

Nadolol protein binding was measured in serum from 95 healthy subjects. Binding was found to range between 4 and 27%, with a mean of 14 +/- 4% (s.d.). There was a small but significant correlation found between the degree of nadolol binding and the serum alpha-1-acid glycoprotein concentration. However it was concluded that changes in the serum protein binding of nadolol were unlikely to give rise to any untoward clinical effects.

DrugBank Data that Cites this Article

Drugs
Drug Carriers
DrugCarrierKindOrganismPharmacological ActionActions
Nadololalpha1-acid glycoprotein (Protein Group)Protein groupHumans
Unknown
Binder
Details