Methadone-induced myoclonus in advanced cancer.

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Sarhill N, Davis MP, Walsh D, Nouneh C

Methadone-induced myoclonus in advanced cancer.

Am J Hosp Palliat Care. 2001 Jan-Feb;18(1):51-3. doi: 10.1177/104990910101800113.

PubMed ID
11406880 [ View in PubMed
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Abstract

Methadone is recommended as being free of some of the neuropsychological side effects noticed with morphine, which are attributed to active metabolites. A patient that received methadone for cancer-associated pain developed myoclonus as a side effect. This has rarely been reported before in the literature. The pathophysiology and management of myoclonus are discussed.

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