The purine path to chemotherapy.

Article Details

Citation

Elion GB

The purine path to chemotherapy.

Science. 1989 Apr 7;244(4900):41-7. doi: 10.1126/science.2649979.

PubMed ID
2649979 [ View in PubMed
]
Abstract

Research on antimetabolites of nucleic acid purines led to drugs for the treatment of acute leukemia (6-mercaptopurine and thioguanine), gout and hyperuricemia (allopurinol), and herpesvirus infections (acyclovir), and for the prevention of organ transplant rejection (azathioprine).

DrugBank Data that Cites this Article

Drugs