The purine path to chemotherapy.
Article Details
- CitationCopy to clipboard
Elion GB
The purine path to chemotherapy.
Science. 1989 Apr 7;244(4900):41-7. doi: 10.1126/science.2649979.
- PubMed ID
- 2649979 [ View in PubMed]
- Abstract
Research on antimetabolites of nucleic acid purines led to drugs for the treatment of acute leukemia (6-mercaptopurine and thioguanine), gout and hyperuricemia (allopurinol), and herpesvirus infections (acyclovir), and for the prevention of organ transplant rejection (azathioprine).
DrugBank Data that Cites this Article
- Drugs