Cytochrome P450 2C9-CYP2C9.

Article Details

Citation

Van Booven D, Marsh S, McLeod H, Carrillo MW, Sangkuhl K, Klein TE, Altman RB

Cytochrome P450 2C9-CYP2C9.

Pharmacogenet Genomics. 2010 Apr;20(4):277-81. doi: 10.1097/FPC.0b013e3283349e84.

PubMed ID
20150829 [ View in PubMed
]
Abstract

Not Available

DrugBank Data that Cites this Article

Drug Interactions
DrugsInteraction
Acenocoumarol
Tolterodine
The metabolism of Acenocoumarol can be decreased when combined with Tolterodine.
Acenocoumarol
Dexibuprofen
The metabolism of Acenocoumarol can be decreased when combined with Dexibuprofen.
Acenocoumarol
Valsartan
The metabolism of Acenocoumarol can be decreased when combined with Valsartan.
Acenocoumarol
Torasemide
The metabolism of Acenocoumarol can be decreased when combined with Torasemide.
Acenocoumarol
Dicoumarol
The metabolism of Acenocoumarol can be decreased when combined with Dicoumarol.
Acenocoumarol
Venlafaxine
The metabolism of Acenocoumarol can be decreased when combined with Venlafaxine.
Acenocoumarol
Hydromorphone
The metabolism of Acenocoumarol can be decreased when combined with Hydromorphone.
Acenocoumarol
Trimethadione
The metabolism of Acenocoumarol can be decreased when combined with Trimethadione.
Acenocoumarol
Treprostinil
The metabolism of Acenocoumarol can be decreased when combined with Treprostinil.
Acenocoumarol
Rosiglitazone
The metabolism of Acenocoumarol can be decreased when combined with Rosiglitazone.
Interactions
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Pharmaco-genomics
DrugInteracting Gene/EnzymeAllele nameGenotypesDefining change(s)Type(s)DescriptionDetails
PhenytoinCytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
CYP2C9*4Not AvailableEffect InferredPoor drug metabolizer, lower dose requirementsDetails
CelecoxibCytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
CYP2C9*4Not AvailableEffect InferredPoor drug metabolizer, lower dose requirementsDetails
WarfarinCytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
CYP2C9*4Not AvailableEffect InferredPoor drug metabolizer, lower dose requirementsDetails
ClopidogrelCytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
CYP2C9*4Not AvailableEffect InferredPoor drug metabolizer, lower dose requirements, higher risk for drug-drug interactionsDetails
Acetylsalicylic acidCytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
CYP2C9*4Not AvailableEffect InferredPoor drug metabolizer, lower dose requirementsDetails
GlipizideCytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
CYP2C9*4Not AvailableEffect InferredPoor drug metabolizer, lower dose requirementsDetails
TolbutamideCytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
CYP2C9*4Not AvailableEffect InferredPoor drug metabolizer, lower dose requirementsDetails
AcenocoumarolCytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
CYP2C9*4Not AvailableEffect InferredPoor drug metabolizer, associated with lower dose requirement.Details
PhenprocoumonCytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
CYP2C9*4Not AvailableADR InferredAssociated with delayed stabilization. If carrier of rs9934438 as well, increased risk of severe overanticoagulation.Details