Clinical pharmacokinetics of doxycycline and minocycline.

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Saivin S, Houin G

Clinical pharmacokinetics of doxycycline and minocycline.

Clin Pharmacokinet. 1988 Dec;15(6):355-66. doi: 10.2165/00003088-198815060-00001.

PubMed ID
3072140 [ View in PubMed
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Abstract

Doxycycline and minocycline are second-generation tetracyclines. They are readily absorbed, distributed throughout the organism as a function of their lipophilicity and eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.

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