Metabolism of 17 alpha-ethinylestradiol by human liver microsomes in vitro: aromatic hydroxylation and irreversible protein binding of metabolites.

Article Details

Citation

Copy to clipboard

Bolt HM, Kappus H, Kasbohrer R

Metabolism of 17 alpha-ethinylestradiol by human liver microsomes in vitro: aromatic hydroxylation and irreversible protein binding of metabolites.

J Clin Endocrinol Metab. 1974 Dec;39(6):1072-80. doi: 10.1210/jcem-39-6-1072.

PubMed ID

4214831 [ View in PubMed

]

Abstract

Not Available

DrugBank Data that Cites this Article

Drugs

Ethinylestradiol

Drug Reactions

Reaction
Ethinylestradiol DB00977 Cytochrome P450 3A4 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 1A2 Cytochrome P450 3A5 2-hydroxyethinylestradiol DBMET00366	Details
Ethinylestradiol DB00977 Cytochrome P450 3A4 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 1A2 Cytochrome P450 3A5 4-hydroxyethinylestradiol DBMET03023	Details
Ethinylestradiol DB00977 Cytochrome P450 3A4 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 1A2 Cytochrome P450 3A5 6-hydroxyethinylestradiol DBMET03025	Details
Ethinylestradiol DB00977 Cytochrome P450 3A4 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 1A2 Cytochrome P450 3A5 7-hydroxyethinylestradiol DBMET03029	Details
Ethinylestradiol DB00977 Cytochrome P450 3A4 Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 1A2 Cytochrome P450 3A5 16α-hydroxyethinylestradiol DBMET03031	Details