Urinary excretion of immunoglobulins and their subunits in human subjects before and after exercise.

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Poortmans JR, Jeanloz RW

Urinary excretion of immunoglobulins and their subunits in human subjects before and after exercise.

Med Sci Sports Exerc. 1993 Feb;25(2):171-8.

PubMed ID
8450718 [ View in PubMed
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Abstract

Immunoglobulins and their subunits in urines collected before and after exercise from healthy human subjects were studied. Quantitative analysis showed that only gamma A- and gamma G-immunoglobulins were excreted as whole molecules in normal urine, at a concentration of 0.35 and 1.70 micrograms/min., respectively. Exercise enhanced the excretion of both types of molecules. In some cases, gamma D-immunoglobulins were found in "exercise urine." Gel filtration on Sephadex G-150 showed that only gamma G-subunits were present in normal and in "exercise urine." The distribution of gamma G-subunits was not affected by exercise. The authors consider the importance of the present data in relation to renal physiology.

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