Aceclofenac in the management of inflammatory pain.

Article Details

Citation

Legrand E

Aceclofenac in the management of inflammatory pain.

Expert Opin Pharmacother. 2004 Jun;5(6):1347-57.

PubMed ID
15163279 [ View in PubMed
]
Abstract

Aceclofenac (Almirall Prodesfarma SA) is an oral NSAID that is effective in the treatment of painful inflammatory diseases and has been used to treat > 75 million patients worldwide. It has proved as effective as diclofenac, naproxen and piroxicam in patients with osteoarthritis, diclofenac, ketorolac, tenoxicam and indomethacin in patients with rheumatoid arthritis and tenoxicam, naproxen and indomethacin in patients with ankylosing spondylitis. It also provides effective analgesia in other indications, such as dental or gynaecological pain, lower back pain and ear, nose and throat indications. Aceclofenac appears to be particularly well-tolerated amongst the NSAIDs, with a lower incidence of gastrointestinal adverse effects. This good tolerability profile results in a reduced withdrawal rate and hence greater compliance with treatment.

DrugBank Data that Cites this Article

Drugs
Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
AceclofenacProstaglandin G/H synthase 1ProteinHumans
Yes
Inhibitor
Details
AceclofenacProstaglandin G/H synthase 2ProteinHumans
Yes
Inhibitor
Details
Drug Reactions
Reaction
Details