Reversal of mydriasis by dapiprazole.

Article Details

Citation

Copy to clipboard

Allinson RW, Gerber DS, Bieber S, Hodes BL

Reversal of mydriasis by dapiprazole.

Ann Ophthalmol. 1990 Apr;22(4):131-3, 138.

PubMed ID

1972008 [ View in PubMed

]

Abstract

The effect of topical dapiprazole, an alpha-adrenergic receptor blocker, in reversing mydriasis was studied in 50 subjects who received tropicamide 1% and phenylephrine 2.5%. There was a significant difference in the decrease in pupil size between the eye that received dapiprazole and the control eye. This study suggests that dapiprazole 0.5% eye drops are effective and safe in reversing mydriasis after instillation of tropicamide 1% and phenylephrine 2.5%.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Dapiprazole	Alpha-1B adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Dapiprazole	Alpha-1D adrenergic receptor	Protein	Humans	Yes	Antagonist	Details