Hutchinson-Gilford Progeria Syndrome: Cardiovascular Pathologies and Potential Therapies.

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Xu S, Jin ZG

Hutchinson-Gilford Progeria Syndrome: Cardiovascular Pathologies and Potential Therapies.

Trends Biochem Sci. 2019 Jul;44(7):561-564. doi: 10.1016/j.tibs.2019.03.010. Epub 2019 Apr 26.

PubMed ID
31036409 [ View in PubMed
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Abstract

Hutchinson-Gilford progeria syndrome (HGPS) is an ultrarare and fatal disease with features of premature aging and cardiovascular diseases (atherosclerosis, myocardial infarction, and stroke). Several landmark studies in 2018-2019 have revealed novel mechanisms underlying cardiovascular pathologies in HGPS, and implicate future potential therapies for HGPS, and possibly physiological aging.

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